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Homoplasy
Homoplasy is the ability of a mutation/variant to emerge independently in different genetic linkages.
Ex. N440K variant of novel Corona Virus found in India, UK, Denmark, Australia.
Independent Emergence of COVID Varients
In a study of 120 unique variants reported in literature based on genome sequencing of the SARSCoV2 virus, the team found that 86 were genetic variants associated with immune escapes. Of the 86 variants, nine had over 1% frequency in the respective countries. Variant N440K : frequency of 2.1% in India, Prevalence in A.P. Identified in UK, Denmark, Australia.an example of Homoplasy. found in healthcare worker, who was reinfected. N501Y : independently emerged in UK, then in South Africa. Made virus more transmissible.
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